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A B12 shot is not a stimulant, so you should not expect a sudden caffeine-like jolt minutes after your appointment

The name comes from its high molecular weight and originally being called a macroglobulin

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When reported, side effects for milk thistle are generally gut disturbances like diarrhea, nausea or bloating

however, it should be emphasized that nutritional compounds have diverse mechanisms of action so this may be an oversimplification

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