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Additional information Responsible Editor: Sami Rtimi Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations

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All three RAMPs can interact with CTR, and this gives rise to three discrete Amy receptor phenotypes, AMY 1 R, AMY 2 R and AMY 3 R, with RAMP1, RAMP2, and RAMP3, respectively 7,8

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