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This has the potential to modulate downstream signalling by directing the ligand towards GLP-1Rs situated in sub-microscopic membrane domains variably enriched with signalling effectors on the cytoplasmic side (Villar et al ., 2016)
Dose escalation to 300 mg should be undertaken cautiously, if at all, in this age group due to increased risk of adverse effects
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Amy Eichner is explaining what you need to know about GLP-1s and how these drugs may impact your young athlete
R.ZhangM
This distinguishes them from the FDA-approved branded versions of these drug classes
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