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Reduces the Symptoms of Parkinsons Disease Parkinsons disease is a well-known neurodegenerative disease with symptoms like motor function loss and cognitive decline, and the second most common neurodegenerative disease in the world
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Expert opinion on drug metabolism & toxicology 5 , 12231244, doi: 10.1517/17425250903143769 (2009)
However, prolonged or complete PERK inactivation can paradoxically increase genomic instability, thereby predisposing cells to tumorigenesis under certain conditions
Exp Mol Pathol 143:104989 Greeck VB, Williams SK, Haas J, Wildemann B, Fairless R (2023) Alterations in Lymphocytic MetabolismAn Emerging Hallmark of MS Pathophysiology
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