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Therefore, SpaMTP offers four complementary strategies to reduce the number of annotations per m / z value (each with user-defined parameters to control filtering): CalculateAnnotationStatistics: This function improves metabolite annotation by incorporating pathway-level correlations derived from spatially resolved omics data (Extended Data Fig

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Protein quantification was carried out using the MaxLFQ algorithm as implemented in the DIA-NN R package ( and the number of peptides quantified in each protein group was counted as implemented in the DiannReportGenerator package ( 71

has made finding possible causes of autism a priority for research, including in May 2025 launching the $50 million Autism Data Science Initiative, and in September 2025 issuing a warning about the potential link between acetaminophen and autism