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N-acetylcysteine, SARS-CoV-2, and male reproduction N-acetylcysteine (NAC) has been proposed as a potential treatment, preventive and/or adjuvant against SARS-CoV-2 as it is having two major activities: first, due to presence of its free sulfhydryl group, NAC reduces the sulfide bonds in the cross-linked glycoprotein matrix in mucus thus reduced mucus viscosity and showing a mucolytic property [20, 21]
The author also thanks the Council of Scientific and Industrial Research (CSIR), New Delhi, for financial support through JRF and SRF
Its sequence incorporates a norleucine substitution, a D-phenylalanine substitution and a lactam bridge that cyclises the molecule, conferring markedly greater resistance to enzymatic degradation than the native linear hormone
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