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The regulatory picture varies and continues to evolve
These kinases possess a modulatory capacity for cellular activities and might phosphorylate transcription regulators, or proteins overseeing gene modulation
In addition to the acquirement of drug-resistant mutation, the development of cancer stem cells also causes CML persistence and relapse from TKI therapy 12,13,14
Xiao et al
doi: 10.1038/s41573-025-01145-0 140 YangXLiuYCaoJWuCTangLBianWet al
A more bioavailable oral version is liposomal glutathione which encapsulates the glutathione in tiny lipid bubbles to protect it from breaking down
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