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Published research on IGF-1 LR3 is indexed on PubMed
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Dulaglutide's REWIND cardiovascular outcomes trial (N=9,901) did show a 12% reduction in major adverse cardiovascular events versus placebo over 5.4 years, which supports its use in patients with T2D and cardiovascular risk
Additionally, IGF-1 enhances expression and activity of enzymes involved in fatty acid metabolism, including carnitine palmitoyltransferase-1, the rate-limiting enzyme for fatty acid entry into mitochondria for oxidation
Dinan TG, Cryan JF
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