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People with existing kidney concerns If you have diagnosed kidney disease (stage 3 or higher), discuss creatine supplementation with your nephrologist before starting
Researchers can introduce specific mutations at the iPSC level using gene-editing technologies such as CRISPR/Cas9 or directly utilize patient-derived iPSCs to generate organoids, thereby reproducing disease phenotypes in three-dimensional structures
Common side effects Nausea Diarrhea Stomach pain Loss of appetite Metallic taste in the mouth Rare or severe side effects Lactic acidosis: This is a rare but serious condition affecting about 1 in 30,000 people , where lactic acid builds up in the bloodstream
doi: 10.1002/jnr.22565 35 McCleanPLParthsarathyVFaivreEHlscherC
When used together, some people may feel more nausea, stomach pain, or acid reflux
Provided for research context not medical advice
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