In a clinical or home-care setting, this kind of reliability is definitely a big deal
Intriguingly, PD-L1, a key immunoregulatory molecule, can act as an RNA-binding protein to stabilize transcripts encoding DDR proteins such as BRCA1, MRE11, and RAD50, thereby enhancing DNA repair and promoting resistance to radiotherapy and chemotherapy
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now provide a direct mechanistic link between neutrophil death and autoimmunity
HEK293T cells were cultured in DMEM + GlutaMAX (Thermo Fisher) supplemented with 10% FBS (Gibco)