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Between 3044 mL/min/1.73 m, metformin can be continued at reduced doses (maximum 1,000 mg daily) but should not be newly initiated
This medication may decrease the effectiveness of hormonal birth control pills, especially when you first start treatment and when the dose is increased
Similar results were found with tirzepatide
MYC target gene sets were globally reactivated following development of resistance to SPA (Supplemental Figure 9D), and MYC reexpression was associated with reexpression of PCAT1 and PVT1 (Supplemental Figure 10A) and reorganization of 8q24 SE accessibility (Supplemental Figure 10B)
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