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In a statement issued by University College London, the trials senior investigator, Thomas Foltynie, characterised the negative result as a major disappointment for patients with Parkinsons disease and for the research community

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For women using hormonal contraception, discussing the bleeding pattern with a GP or sexual health specialist may lead to adjustments in contraceptive method or formulation

(8.2) Females and Males of Reproductive Potential: For patients receiving WEGOVY for CV risk reduction or weight reduction, or for MASH where the potential risk outweighs the potential benefit, discontinue WEGOVY at least 2 months before a planned pregnancy because of the long half-life of semaglutide

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One argument is that, by lowering lifetime healthcare costs, these drugs will actually save a lot of money, Abaluck says