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Nanocarrier uptake in human brain endothelial cells and midbrain organoids was quantified by spectrofluorometry and visualized by confocal microscopy
Eighteen adult, female New Zealand white rabbits, all physically normal and weighing an average of 2.5 kg, were used
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Animal Model and Ethics Statement Wistar rats from the breeding colony at the Universidade do Extremo Sul Catarinense (UNESC), Brazil, were housed four times per cage under controlled conditions of temperature (22 1 C), relative humidity (4555%) and light-dark cycle (12:12 p.m., light on at 6 a.m.)
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In the tirzepatide group, people had an average of 30.4 fewer apnea events per hour, compared to an average reduction of six events per hour in the placebo group
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