Achieving a durable and efficient antiangiogenic response will require approaches to simultaneously or sequentially target multiple aspects of the tumor microenvironment
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Wetzler M, Wang ES, Shepard R, Thomas DA, Andreeff M , O'Brien S, Kantarjian HM
From a structural standpoint, the presence of a GHK triplet in the alpha 2(I) chain of type I collagen suggests that the tripeptide might be liberated by proteases at the site of a wound and exert in situ [recovery], pointing to a possibly autocrine or paracrine regulatory role within the extracellular matrix environment
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Glutathione is found naturally in every cell and made within the body, specifically in the liver