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Effects of canagliflozin on amputation risk in type 2 diabetes: the CANVAS Program

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Approximately 5-10% of patients lose less than 5% of body weight despite adequate dosing and treatment duration

They also revealed that the reduction in the axon/fibre area ratio of the sciatic nerve and intraepidermal nerve fibre loss were relieved by exendin-4 injection (49)

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the patient should be in a #rested, non-stressed state