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AOD9604 has been studied in preclinical and early clinical settings, and it received GRAS (Generally Recognized as Safe) designation from the US FDA for use as a food ingredient
Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression
p21 produces a bioactive secretome that places stressed cells under immunosurveillance
Peptides for Healing: What the Evidence Shows Peptides for healing by tissue: tendon, bone, wound, gut, post-surgery
My honest opinion: the signal is strong enough to warrant formal study, and it's frustrating that the economics of peptide research make that unlikely anytime soon
Interestingly, the presentation of DAPT and BMS appeared to exert the opposite action to TB-500, suggesting that the Notch/NF-B pathways may mediate TB-500s proposed action on angiogenesis
![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
