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If carbamazepine is not effective or causes side effects, oxcarbazepine or a combination therapy with gabapentin/pregabalin or baclofen can be introduced to improve pain control with fewer adverse effects

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NF-B Pathway Inhibition KPV directly suppresses the NF-B inflammatory signaling pathway the master regulator of inflammatory gene expression

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Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination

Postnatal Supplements As evident in Table 2, there is high variability both between the components of prenatal and postnatal supplements and within these groups themselves