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Source: Jastreboff et al., NEJM 2023 TRIUMPH-4 Phase 3 (68 weeks, 445 participants) Phase 2 Type 2 Diabetes Trial (36 weeks, 281 participants) In the type 2 diabetes population, weight loss was lower than in the obesity trial which is consistent with the pattern seen across all GLP-1 drugs

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doi:10.1038/s41586-019-1537-0 43

Start your intake Why Tirzepatide Causes Sulfur Burps Tirzepatide slows gastric emptyingthe rate at which your stomach moves food into the small intestine

Your metabolic rate drops