Excess weight often triggers chronic inflammation in the body, which can worsen joint pain and stiffness
Dig Dis Sci 50:13721375
But what Semaglutide actually does to your body is devastating, not just dangerous
Semaglutide withdrawal itself can cause its own set of symptoms, including appetite rebound, temporary weight regain, and changes in GI function as the body readjusts to normal gastric emptying speed
However, the percentage of body weight lost tends to be similar across BMI categories at 12 and 24 months, suggesting that the medication's effect on appetite is proportionally consistent regardless of starting weight
Accordingly, these findings indicate that, in certain contexts, increased GLP-1 can negatively affect myogenic differentiation and muscle metabolic performance [83]