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The discovery of insulin revisited: lessons for the modern era

PLoS Med 4(6): e206

Hormone changes can lead to high blood pressure and other risk factors for heart disease

All-trans retinoic acid (ATRA), the most common metabolite of vitamin A, promotes transcriptional activation of differentiation-associated genes and plays an important role in the treatment of cancer, dermatological disorders, acute promyelocytic leukemia (APL), and MTB infections (122)

Ethics declarations Conflict of Interest Raj Chovatiya has served as an advisor, consultant, speaker, and/or investigator for AbbVie, Acelyrin, Alumis, Amgen, AnaptysBio, Apogee Therapeutics, Arcutis Biotherapeutics Inc., Argenx, Astria Therapeutics Inc., Avalere Health, Beiersdorf, Boehringer Ingelheim, Bristol Myers Squibb, Cara Therapeutics, Castle Biosciences, Celldex CLn Skin Care, Dermavant, Eli Lilly and Company, EMD Serono, Formation Bio, Galderma, Genentech, GSK, Incyte, Johnson & Johnson, Kenvue, LEO Pharma, LOral, Nektar Therapeutics, Novartis, Opsidio, Pfizer Inc., RAPT, Regeneron, Sanofi, Sitryx, Takeda, TRex Bio, UCB, and Zai Lab

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