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Low blood sugar (hypoglycemia): Your risk for getting low blood sugar may be higher if you use Tirzepatide with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin

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Factors to consider include: Kidney damage: Ozempic may cause severe dehydration as a complication of nausea, vomiting, and diarrhea during treatment

doi: 10.1016/j.eclinm.2026.103796