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However, there are a few downsides to consider: Invasive: Receiving regular injections may be uncomfortable for some people, as it requires visiting a clinic or performing self-injections

Nasal administration is not well studied, 1 and the difference in effect on B12 levels amongst individuals may be due to the route of administration

It simply means your body may benefit more from pre-methylated forms of folate and B12

[3] Those with Leber's disease (hereditary optic neuropathy) should avoid cyanocobalamin formulations

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In some cases, the condition may improve over time, while in others, it can remain constant or even worsen due to increased stress levels or other health changes associated with aging