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Interestingly, the dual agonist tirzepatide has shown efficacy in neuroprotection, by counteracting hyperglycemia and insulin resistance-related effects at the neuronal level ( Also triple agonists have demonstrated to possess anti-neurodegenerative properties, indicating a potential for treating Alzheimers disease by reducing neuroinflammation and oxidative stress, enhancing neuronal health and viability, and minimizing glutamate excitotoxicity (Kopp et al., 2022)

Intravenous, or infusion, therapy is an alternative or addition to oral treatment

Compounded tirzapetide is no longer on the market, and compounded semaglutide will be removed by April 22 for state-licensed 503A pharmacies or May 22 for larger 503B pharmacies

doi: 10.1016/j.xcrm.2021.100387 104 ArodaVRAberleJBardtrumLChristiansenEKnopFKGaberySet al

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Pay attention to the scale If daily weigh-ins feel stressful, talk with your health care provider about a monitoring schedule that works for you