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Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis
As shown in Figure 3A, reduced expression levels of IL-6 and 8 and MMP3, 12 and 13 were observed in the FOXO4-DRI treated group, which however were concomitantly accompanied with reduced expression of SOX9 and COL2 , as well as increased expression of CDKN2A, CDKN1A , and TP53 (encoding p53)
doi: 10.1007/s00401-022-02497-2 111 Matute-BlanchCBritoVMidagliaLVillarLMGarcia-Diaz BarrigaGGuzman de la FuenteAet al
Extracellular matrix remodeling: pre-clinical models examine collagen organization, fibroblast activity, and tendon/ligament matrix response during repair-phase research
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Most patients settle into two substantive meals and one or two small ones (a handful of almonds, a protein shake, a piece of cheese)
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