Several other metabolites that were reduced in this studysuch as oxalic, tartaric, pyruvic, and lactic acidhave been reported to influence mitochondrial function by promoting the generation of reactive oxygen species (ROS) and a shift toward anaerobic metabolism
In in vitro experiments, NRF2 expression was reduced in IL-22-stimulated HaCaT cells, while the addition of SFN partially restored NRF2 expression
Related reading: toxic overload, elevated SAH and impaired methylation
Well-known vitamins and minerals such as magnesium, calcium, and vitamin C are just a few examples
Vitamin D3 (cholecalciferol)
Li BT, Michelini F, Misale S, Cocco E, Baldino L, Cai Y, et al