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demand as we hope to set a new treatment benchmark for oral weight loss medications for people with overweight or obesity, he added

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Rigorous, long-term prospective trials in asymptomatic, high-risk populations such as individuals with type 2 diabetes, obesity, or APOE4 carrier status are required to definitively validate or refute this hypothesis

Establish nutrition and lifestyle habits during GLP-1 use so they are easier to sustain if treatment stops

Although low dose capsaicin was applied to selectively ablate gastric vagal afferents, a method well established in pharmacology, the overall toolkit for targeted vagal afferent manipulation remains limited [62]