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Methods Reagents and chemicals All chemicals and reagents were purchased from Fisher Scientific (Hampton, NH) or from Sigma-Aldrich (St

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Obesity is a significant health problem among teachers, with one study finding that 70.2% of female school teachers have obesity

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Worsening intracellular oxidative potential was accompanied by increases in intracellular expression of downstream T2 signature proteins, such as POSTN and CCL26, with nonsignificant increases in inducible NO synthase (iNOS/NOS2

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Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations 8-OH-dg: 8-hydroxy-2-deoxyguanosine AM: airway macrophage BAL: bronchoalveolar lavage ELF: epithelial lining fluid GSH: glutathione (reduced form) GSSG: glutathione disulfide (oxidized form) HAT: histone acetyltransferase HDAC: histone deacetylase ICS: inhaled corticosteroid MDA: malondialdehyde PARP: poly (ADP-ribose) polymerase References Fitzpatrick AM, Gaston BM, Erzurum SC, Teague WG 2006 Features of severe asthma in school-age children: atopy and increased exhaled nitric oxide

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