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Huntingtons disease is a rare progressive hereditary neurodegenerative disorder whose symptoms include uncontrolled movements, cognitive decline, and psychiatric issues

Takaso, Y

Telomerase is an enzyme involved in maintaining telomeres, which are protective structures at the ends of chromosomes

Subcutaneous injection remains the preferred administration route for systemic effects, providing 90-95% bioavailability

Three RCTs met inclusion criteria The trials randomized 153 participants (74 participants to oral vitamin B12 and 79 participants to IM vitamin B 12 )

Clarke R, Daly L, Robinson K, Naughten E, Cahalane S, Fowler B, and Graham I (1991)