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Without adequate CoQ10, this conversion process slows down.*
Using a model of induced DSBs in an endogenously CCNE1 overexpressing cell line (Tang et al., 2013), we found increased DSBs upon IDH1i treatment, which was rescued by KG and L-carnitine ( Fig
These side effects are generally manageable and can be minimized by starting with a lower dose and gradually increasing it as tolerated
Cells 10:971
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