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Antiox Redox Signal 15, 3947
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310 In age-related diseases, metformin beneficially enhances mitochondrial function, increases Nrf2 activity, induces autophagy, or ameliorates accelerated aging defects in HutchinsonGilford progeria syndrome (HGPS) cells by altering gene splicing through its activation mechanisms
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PBMC pellets were resuspended in Roswell Park Memorial Institute (RPMI)-medium without additives
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