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The capsules are well-designed, and theres no harsh aftertaste
This article provides a comprehensive review of DSIPs biological mechanisms, potential benefits, dosage considerations, comparative efficacy, and current research data
Thank you Michael Albert MD for sharing
"And even within Reddit, the people who post about their side effects are probably not typical of everyone on the medication," Sehgal said
Effects: * LDL cholesterol * Triglycerides * HDL cholesterol * Stabilizes atherosclerotic plaques * Reduces inflammation in blood vessels Indications * Hypercholesterolemia * Mixed dyslipidemia * Familial hypercholesterolemia * Prevention of: * Myocardial infarction * Stroke * Cardiovascular disease Used in patients with: * Diabetes mellitus * Hypertension * Atherosclerotic cardiovascular disease Dosage Typical adult dose: * 540 mg once daily Common starting doses: * 1020 mg daily * Lower doses in: * Elderly * Renal impairment * Asian patients Maximum: * 40 mg/day Pharmacokinetics * Oral administration * Long half-life (~19 hours) * Mainly hepatic action * Excreted partly unchanged in feces Adverse Effects Common * Headache * Myalgia * Abdominal pain * Nausea * Constipation Serious * Myopathy * Rhabdomyolysis * Hepatotoxicity * New-onset diabetes (rare) Monitoring Before and during therapy: * Lipid profile * Liver function tests * CK level if muscle symptoms occur Contraindications * Active liver disease * Pregnancy * Breastfeeding * Severe hypersensitivity Statins are contraindicated in pregnancy because cholesterol is important for fetal development
Hormonal shifts regulate adipogenesis and browning of fat
