At Josie, we like to taper down in doses with our patients, so your body can adjust accordingly
Record the consensus plan in the chart, with last-dose date, planned surgery date, and justification so anesthesia, surgery, and perioperative medicine teams have a unified timeline
doi: 10.1073/pnas.84.10.3434
And weve seen data that suggests that even doses as low as 0.1 to 0.2 milligrams, which is even lower or at the starting dose for our microdose program are showing reductions in fasting blood sugar and also in CRP, which is C-reactive protein, which is one of the primary markers of inflammation
clinical standards
This is the quiet reason so many well-designed nephrology trials struggle - not a shortage of patients, but the difficulty of finding the specific ones who actually qualify, buried across years of fragmented EHR data