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In one study, patients who received Sermorelin for 12 weeks experienced an increase in lean body mass and a reduction in body fat

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Specifically, the inhibition of Nrf2 ubiquitination increases nuclear Nrf2 retention and ARE-Nrf2 binding affinity (Rizvi et al., 2015a)

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1a), and all treatments lead to decreased cell viability, as measured by annexin V-PI assay (Fig