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Gallbladder-related symptoms: Sudden severe pain in the upper right abdomen Pain between shoulder blades Nausea with right upper quadrant tenderness Semaglutide increases gallstone risk, and symptoms may require imaging and possible surgical intervention

Diagnosis typically involves physical examination, patient history, and imaging studies like X-rays, MRI, and sometimes CT scans

Pruritus was reported in 4%, 2%, and 2% of patients (including adolescents) receiving topiramate 50 mg/day, 100 mg/day, and 200 mg/day, respectively, for migraines in placebo-controlled (2%) clinical trials

Extended-release versions may cause fewer digestive issues