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Nat Rev Dis Primers 2:16057
Journal of Clinical Endocrinology & Metabolism (2023)
Under the stimulation of insulin, pancreatic fat consistently secretes inflammatory factors such as IL-6, TNF to alter chronic inflammation in the pancreas, which finally leads to oncogenic mutation and the onset of PDA (Klting and Blher, 2014
Some people achieve excellent results with semaglutide and see no reason to spend extra for tirzepatide
While the choice is up to you, having the right guidance is key
In a few specialised situations a diabetes specialist may consider adding them to insulin in carefully selected people, but this is off-label and needs close monitoring
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