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For example, Advan's foot traffic data shows McDonald's visit frequency to be 70% higher than Olive Garden's
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Elevated pro-inflammatory cytokines (e.g., IL-6, TNF-) and dysregulated matrix metalloproteinases (particularly MMP-9) degrade extracellular matrix components and interfere with endothelial signaling, while reduced TIMP levels further exacerbate vascular dysfunction
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Fatigue can stem from inadequate protein intake, dehydration, poor sleep, or other factors unrelated to NAD+ levels
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