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The exact cause of IBS remains incompletely understood, but contributing factors include visceral hypersensitivity (increased pain perception in the gut), altered gut motility, changes in the gut microbiome, low-grade inflammation, and psychological factors such as stress and anxiety
Both medications share the same gastrointestinal side effect profile, with nausea as the most common complaint
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Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial-the Losartan Heart Failure Survival Study ELITE II
