Sitagliptin Add-on Therapy in Patients with Type 2 Diabetes Inadequately Controlled on Metformin Alone In a 24-week placebo-controlled trial of sitagliptin 100 mg administered once daily added to a twice daily metformin regimen, there were no adverse reactions reported regardless of investigator assessment of causality in 5% of patients and more commonly than in patients given placebo
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Clinical trials expanding The success of GLP-1 agonists has validated peptides as a therapeutic class
Fontes-Dutra M, Santos-Terra J, Deckmann I, Brum Schwingel G, Della-Flora Nunes G, Hirsch MM, Bauer-Negrini G, Riesgo RS, Bambini-Jnior V, Hedin-Pereira C, Gottfried C
doi.org/10.1002/ibd.20453 Seiwerth, S., et al