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In brief, there are many shared biological processes between the effects of mental stress and the mechanisms underlying age-related vascular dysfunction

Vitamin D (if deficient) plays a role in fat metabolism and should be optimized before starting any fat loss protocol

Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells

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Oral bioavailability is expected to be negligible given the peptide's large size, and subcutaneous or intravenous delivery would likely be required for any human application

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