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In previously healthy individuals over 50 who experience the sudden onset of diabetes, and in those patients with newly diagnosed chronic pancreatitis who also present with weight loss, glycemic decompensation, abdominal pain, and other abdominal symptoms, a one-time assessment using high-resolution pancreatic imaging (MRCP or EUS) is warranted to rule out the possibility of occult PDAC

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PMID: 18519800

Mechanism of Action of Semaglutide Semaglutide helps by acting like a hormone called GLP-1, which is produced in the intestines

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The question is whether the category scales beyond the narrow population for whom the top-line number is observed under clinical-trial conditions