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j , n = 6, two-sided unpaired t-test)
As can be seen from Volcano Figure 11 , the FI group up-regulated 31 differential metabolites and down-regulated 2 differential metabolites relative to the NC group
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In renal tubular epithelial cells treated with calcium oxalate (CaOx) to induce kidney stone formation, CHAC1 expression increases alongside a decreased GSH level, reduced GPX4 activity, increased iron and MDA content and elevated ROS and lipid peroxidation
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