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Don't use it if you see particles or discoloration
The SURMOUNT-1 trial enrolled 2,539 patients with obesity, excluding individuals with diabetes or uncontrolled hypertension, and randomized them to placebo or 5, 10, or 15 mg of tirzepatide
In a 2025 study published in Obesity Medicine , 52% of patients who discontinued GLP-1 therapy cited adverse effects as the main reason
Redistributing filler In certain cases, practitioners can sometimes adjust the filler than completely dissolve it
Continue at the reduced dose for two to four weeks and assess
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