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If additional glycaemic control is needed, the dose may be increased to 1 mg weekly and up to a maximum of 2 mg weekly
It regulates genes involved in hormone production and ovulation
Indirect DNA damage caused by the slow energy dispursion from the chromophores creating hydroxyl radicals
By managing blood sugar levels and addressing underlying risk factors, tirzepatide may help individuals with diabetes reduce their overall cardiovascular risk and improve their heart health
BMI 35.0 to 39.9 (class II obesity)
Initially approved for type 2 diabetes (T2D) treatment, they were later found to influence appetite regulation (145, 146) by regulating activity in hedonic brain regions like the insula and orbitofrontal cortex changing food preference (147), therefore, leading to their approval for obesity and diabetes management (148150)
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