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Routine B12 monitoring is not mandated for tirzepatide, but baseline and periodic testing should be considered for high-risk patients, including those over 65, on concurrent metformin, with gastrointestinal disorders, or experiencing symptoms such as fatigue, neuropathy, or cognitive changes
[25] Major abdominal, thoracic, or orthopaedic surgery generally requires waiting until the patient has returned to normal bowel function and can maintain adequate oral nutrition without significant nausea before reintroducing medications that may suppress appetite or delay gastric emptying
Its very individualized
But heres something most people dont realize right away: its not just about taking it, its about how your body uses it