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2016 May;23(5):461-7

Strauss AS, Peters S, Boland W, Burse A

IL-5 is mainly produced by T helper (Th2) and mast cells and stimulates B cell growth and activation, increasing antibody production [76]

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Notably, emerging evidence reveals that HIF-1 transcriptionally activates heat shock factor 1 (HSF1), the master regulator of the heat shock response [56, 57]