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Glutaredoxins (Grx) are small redox enzymes that are oxidized by their substrate and use GSH as a regenerator reducing substrate
Together, they address four of the five pillars of tissue regeneration
J Neuropathol Exp Neurol 69:155167 Sultana R, Piroddi M, Galli F, Butterfield DA (2008) Protein levels and activity of some antioxidant enzymes in hippocampus of subjects with amnestic mild cognitive impairment
Gene (2020) 724:144144
Twice daily application is well-tolerated
Differential impact of glucose levels and advanced glycation end-products on tubular cell viability and pro-inflammatory/profibrotic functions
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