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NEJM 2022 FDA Approves New Drug Treatment for Chronic Weight Management (Wegovy) FDA Approves New Medication for Chronic Weight Management (Zepbound) Frias JP et al
Adjustment Phase: Patients complete monthly updates, allowing dosage adjustments based on progress and side effects
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Los participantes del ensayo clnico que tomaron tirzepatida, el medicamento vendido como Zepbound, perdieron 22,8 kilogramos (50 libras) en promedio durante 72 semanas, mientras que aquellos que tomaron semaglutida, o Wegovy, perdieron alrededor de 15 kilos (33 libras), de acuerdo con el estudio financiado por Lilly y que fue publicado en el New England Journal of Medicine
Other notable limitations include that about 15% of participants did not complete the trial and small sample size to detect rarer adverse events or conduct subgroup analyses
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