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The following strategies are essential during combination therapy
On long trips, get up every one to two hours and flex your calves and feet while seated to keep venous return strong
Some PlexusDx patients use dedicated pharmaceutical-grade freezers or lab freezers for more predictable temperature control, though a standard household freezer works perfectly fine
Does it cause functional impairment
Maintain adequate hydration (68 glasses daily), time fluid intake to reduce nighttime urination, keep a symptom diary, review blood glucose control with your healthcare team, and consider pelvic floor exercises if urgency is problematic
