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Discussion PD is a commonly occurring neurodegenerative disorder that produces muscular rigidity, bradykinesia, tremor in resting limbs and loss of postural balance 1,39

The clinical titration starts at 0.25 mg weekly and increases every four weeks up to a maintenance dose of 2.4 mg weekly, though some research protocols extend up to 4.5 mg

Cells have a number of properties that allow them to resist the damaging effects of ROS and APs effectively [12-19]