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[13] This trial was conducted in 20 countries: multiple European countries, Russia, Turkey, Brazil, Israel, Malaysia, Mexico, Thailand, Taiwan, Canada, and the United States

Moreover, the increased melanin levels induced by this combination provide a natural defence against harmful UV rays, potentially reducing the risk of sunburn and skin damage

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Presented for research literature review only Kong PJ et al

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In research settings it is used to investigate melanocortin receptor (MC1RMC5R) signaling and pigmentation pathways